Scientists have uncovered a natural braking system that helps the immune system switch off inflammation and prevent harmful immune cells from building up. Boosting this pathway in people reduced inflammation-related immune changes and sped up pain relief, pointing toward potential new treatments for chronic inflammatory diseases.

First author Dr. Olivia Bracken (UCL Department of Ageing, Rheumatology and Regenerative Medicine) said: "Our findings reveal a natural pathway that limits harmful immune cell expansion and helps calm inflammation more quickly.

“Targeting this mechanism could lead to safer treatments that restore immune balance without suppressing overall immunity. With chronic inflammation ranked as a major global health threat, this discovery opens a promising avenue for new therapies.”

  • Em Adespoton@lemmy.ca
    11·
    17 hours ago

    I’ve been using a phosphdiesterase inhibitor for the past year and it’s a game changer. Expensive though, unless your insurance covers it.

    This is a step further up the chain, which should mean fewer side effects and a more general effect on the entire system. And it’s with an already approved drug.